2 Peter 2:12

These. That is, the false teachers. Compare the parallel passage in Jude 10.

Natural brute beasts. Or, “irrational creatures.” The word translated “beasts” is zda, “living creatures” (see on Rev. 4:6).

To be taken and destroyed. Literally, “for capture and destruction.” Peter’s devastating description emphasizes the irrational and unspiritual nature of these lascivious deceivers.

Speak evil. Gr. blasphemed, “to blaspheme,” “to speak evil against.” Compare the use of blasphemed in vs. 2, 10, and of the adjective blasphemos, “slanderous,” “blasphemous” in v. 11.

Things. The clause reads literally, “in which things they are ignorant” (cf. 1 Tim. 1:7). The deluded ones could have gained an understanding of divine matters, but chose to remain in ignorance and to lead others astray.

And shall ... corruption. Rather, “in their perishing also they shall perish.” There is a play upon words in the Greek that is not brought out in the KJV. The writer may be suggesting that the false instructors will perish as do the animals, or that they will perish as a result of their own corrupt doings. Both interpretations are valid, and the end is the same — the teachers will be destroyed.