Genesis 6:3

My spirit shall not always strive. The fact that this statement follows immediately after the reference to these unsanctified marriages would suggest that God’s displeasure was most particularly displayed toward this evil practice. Captive to their passions, they were no longer subject to God’s Spirit. The word “strive” in the Hebrew means “to rule,” and “to judge,” as corollary to ailing. These words indicate that the Holy Spirit could continue working but a little longer, and would then be withdrawn from the unregenerate and unrepentant of the human race. Even God’s long-suffering must end. Peter refers to the work of the Spirit on the hearts of the antediluvians, saying that the Spirit of Christ preached to these prisoners of Satan (1 Peter 3:18-20).

For that he also is flesh. This expression may also be translated, “in their going astray man is flesh,” from shagag, “to wander,” “to go astray.” By following after the lusts of the flesh, says God, men have surrendered themselves to its desires to the extent that they are no longer responsive to the control of the Holy Spirit. Insensibility to divine influence is complete; hence, the Spirit of God is to be withdrawn. There is no further use in “striving” to restrain or improve them.

His days. This divine prediction cannot mean that man’s life span would henceforth be restricted to 120 years. (Compare ages of men after the Flood.) They predict, rather, that God’s patience would come to an end and probation close within the period of time here specified. In the meantime, divine mercy lingered.

Christ compared God’s dealings with the antediluvians to His work for the human race at the end of time (Matt. 24:37-39). Under similar circumstances God may be expected to work in similar ways. However, attempts to determine the time of Christ’s coming on the basis of this are wholly invalid. We are now living on borrowed time, knowing that the destruction of the world will soon occur (see 2 Peter 3:3-7). We know also that God’s Spirit will not endlessly strive with men who do not choose to heed His warnings and prepare for that great event.