Isaiah 6:3

Holy, holy, holy. The angels about the throne of God are impressed with His outstanding attribute — perfect holiness of character. The living creatures John saw about the throne likewise cried, “Holy, holy, holy, Lord God Almighty” (Rev. 4:8). God sought to impress upon the mind of Isaiah a concept of His holiness, in order that the prophet should keep this attribute of the divine character constantly before His people, that they might thereby be encouraged to put away their sins and aspire to holiness. The Dead Sea scroll 1QIs (see Vol. I, p. 31; Vol. IV, p. 86) omits the words “and said,” and has the word “holy” twice only.

Full of his glory. Compare ch. 40:5. A realization of the glory and holiness of God will lead men to stand in humility before Him. At a time when darkness covered the earth and gross darkness the people (ch. 60:2), Isaiah looked forward to the hour when all the earth will be covered with God’s glory.